Blood ESR stands for Erythrocyte sedimentation rate while anticoagulated blood is left settled for a period of your time, the erythrocyte tends to sink to rock bottom. Two layers are form, the upper plasma layer, and therefore the lower RBC layer. The rate at which the red cells fall is understood as ESR.
There are the following important features of ESR determination are :
- The changed levels of protein like fibrinogen, CRP, and globulins which occur due to
most of the accute and chronic infections tend to extend the rouleaux formation.
Albumin decreases the erythrocyte sedimentation rate. ESR is therefore increased in any condition causing a rise in fibrinogen due to any tissue breakdown like TB(tuberculosis)
or albumin increase in many chronic diseases.
- In hypochromic anemia, the microcytes hold rouleaux formation because to which sedimentation rate
- ESR is more prominent in ladies than men.
- While pregnancy ESR casually increases after 3rd month and returns to normal in about
3 to 4 weeks after birth.
- ESR level is low in infants and easily increases up to puberty. Its lowered until old age and suddenly again raised.
What is ESR Test?
ESR test is a sort of test which estimates how the RBC’s falls inside the tube in which your blood sample is taken and the ESR test value grows up only when there is any swelling (Inflammation) or tissue damage.
Now let's understand how the ESR test is done
The ESR test is performed in labs that use one of the two methods, one is Westergen’s tube and the other is the Wintrobe Tube method. But the ESR test results of both methods are correct but depending on the lab what method he doing.
There is a fasting requirement to conduct the ESR Test?
You needn’t worry about any extraordinary preparations for this test. But if your doctor says to stay fasting, then you will go through fasting and get tested.
What Happens If the Erythrocyte Sedimentation Rate is High?
See sometimes ESR test increased when tissue breakdown or mild infections or entry foreign proteins into the blood or patient is taking some medicine for a long time. When you suffered some health problems then your doctor order you to diagnose the ESR test. The test results of ESR are normal or high and average, however, not diagnostic of any specific disease.
- Accute and Chronic Infection
- Sickle Cell Anemia
- Plasma Factor- Fibrinogen increase the ESR rate, Plasma Albumin decreases the sedimentation rate.
- Red Cell Factor- The number of high blood count lower the sedimentation rate whereas low blood count increase the sedimentation rate.
- Size- Microcytes sediment slowly and Macrocytes sediment rapidly.
- Shape- The shape of the RBC’s can also affect the ESR sickle cell decrease cell the ESR rate because sickle cell prevents the rouleaux formation.
- Pregnancy- The ESR begins to increase the after 3rd month and return to normal 4th week after delivery.
- Age- In infants ESR gradually low and in an adult, a person increases ESR shows and an older person’s ESR shows higher.
- Gender- Women have higher ESR than men.
- Temperature- Higher temperatures cause falsely high results. The test should be done at 25 – 25 degrees Celcius.
- Tube Factor- ESR is greater than the longer tube.
- Hemolysed or Clotting Factor- It decreases the ESR.
- Time- Test should be done within 2 hours o the collection in EDTA Vial or BLACK top tube Vial (contain 3.8 sodium citrate anticoagulant) sample should be kept at 4 degrees Celcius but it must be performed within 6 hours.
- Sunlight- Direct sunlight in an ESR tube increase the ESR.
- Position of Tube- Tube should be perfectly vertical even minor lifting can cause higher ESR.